Cell Analysis Blog

Decoding Cells:

A Cell Analysis Blog

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In our fight against viral pneumonia, the “Mighty Macrophage” packs a punch

March 30th, 2020

Macrophages have always been a favorite of immunologists. With their bigger-than-life presence under the microscope, who can resist their charm as they gobble up pathogens, and clear erythrocytes and cellular debris like giant cellular garbage trucks?

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Video: IncuCyte® Spheroid Analysis Software Module

March 27th, 2020

The IncuCyte® Live-Cell Analysis System and IncuCyte® Spheroid Analysis Software Module, provide a robust solution for analyzing metastatic potential of solid tumors. With integrated, label-free analysis, single spheroid invasive capabilities can easily be quantified undisturbed, for days or weeks, delivering physiologically relevant pharmalogical information.

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Five Exciting Cell and Molecular Biology Discoveries from 2019

February 10th, 2020

Lori King PhD takes a look back at innovations which resonate with herself. These techniques may herald new eras in Cell and Molecular Biology, with the ultimate aim of producing new treatments for existing diseases, and perhaps also opening new frontiers in the Biosciences.

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SelectScience Gold Award 2019

January 21st, 2020

IncuCyte® Live-Cell Analysis Systems have been awarded the prized SelectScience® Seal of Quality Gold award. The successful Seal of Quality program aims to help scientists across the world, quickly see the top rated peer reviewed products on the market. Only 0.1% of laboratory products that consistently receive the highest customer review ratings, may be considered for the award.

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Software: Identify where the cells within your gate fall in the all events plot, using the "Back Gate"

December 13th, 2019

Back gating helps to identify where the cells within your gate fall, within the all events plot. Back gating helps confirm your gating strategy, particularly for forward scatter vs. side scatter.

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Uncovering the Secrets of Cellular Motility: The Impact of Actin Nt-Acetylation on the Cytoskeleton

December 9th, 2019

Cellular motility in animals is a dynamic process, dependent on the interactions of microfilaments (e.g. actin and myosin), intermediate filaments (e.g. keratin), and microtubules. Working together in concert, these cytoskeletal structures engage in cellular activities such as cellular migration, transportation of vesicles, and gene transcription to name a few. In particular, the actin protein is a busy player; shuffling states between polymerization at the leading edge of cells to help pull them forward, and depolymerization at the trailing edge, pushing them from behind.

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Live Cell Analysis for Neuroscience Research

December 5th, 2019

Susana Alcantara, Senior R&D Scientist and Neuroscience Program Leader, BioAnalytics, of Sartorius, chatted with Brandy Sargent of Cell Culture Dish about how real-time live cell analysis is enabling neuroscience research.

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CRISPR: uncovering clues with off-target therapeutic implications

November 7th, 2019

Exploiting bacterial defense mechanisms has led to the development of CRISPR technology for gene editing and identification. CRISPR has become a popular research tool in the fight against cancer, neurological disease, heart failure, and other rare conditions in desperate need of new therapeutic options. With new technology, however, comes new questions: one being how to best to monitor possible off-target effects that might arise from experimental manipulations and determine the factors that contribute? This is not an easy question to answer.

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Software: Automatically identify populations of interest with 'Smart Gate'

October 29th, 2019

Gates used during flow cytometry data analysis aren’t 100% accurate even with a template. The integrated ForeCyt® Software on the iQue3 advanced flow cytometry platform addresses this issue with “Smart gate”, which automatically identifies the population of interest by centering itself on the closest dense area on the graph.

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Real-time visualization and quantification of neutrophil activation and function using Live-Cell Analysis

October 18th, 2019

Here’s a chance to see a poster presentation come to life. The poster was originally displayed at the annual meeting of the American Association of Immunologists (AAI) 2019.

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