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Decoding Cells — The Blog

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White Paper: Live-cell Analysis for Neuroscientists

January 18th, 2019

In this article, we discuss several neurobiology-specific applications using live-cell analysis to assess such processes as basic iPSC-derived neuronal cell health, neurite dynamics, neuronal activity, and microglial phagocytosis and chemotaxis. These assays are noninvasive, nonperturbing, and cell sparing, thus providing a valuable complement to other end-point techniques.

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White Paper: Unraveling the Complexities of Neurological Disease and Injury with Real-time Live-cell Analysis

January 18th, 2019

In this whitepaper learn, how real-time live-cell analysis could be a valuable tool for use in neurological disease model development, the study of disease pathology, neuroinflammation, nervous system injury, and drug discovery.

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Trapping Microbes: Live-Cell Visualization of NETosis

January 14th, 2019

As first responders against pathogens, the neutrophils migrate from the blood to the infected site to engulf and kill bacteria. In 2004, it was discovered that neutrophils can also kill microbes extracellularly by releasing neutrophil extracellular traps (NETs).

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Video: IncuCyte Poster Snapshots | Quantitative Live-Cell Imaging Assays for Immunotherapy

December 21st, 2018

Watch as Nicola Bevan walks us through this scientific poster: Quantitative live-cell imaging assays for immunotherapy: chemotaxis, immune cell killing & phagocytosis. Presented at CIMT 2016, Germany

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Video: The Brave New World of Immuno-Oncology

December 21st, 2018

To develop and validate next generation immuno-oncology therapies researchers have a need to study the basic functions of tumor and immune cells in isolation and together. In vitro tumor cell proliferation, migration and invasion assays enable the assessment of cancer cell growth and metastatic potential. Immune cell activation and chemotactic migration assays are used to study how the body mobilizes its forces against foreign cancer cells. Models of immune cell killing and tumor cell clearance are used to characterize therapeutic activity.

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Video: Why is Cell-by-Cell Analysis Important?

December 21st, 2018

Answer more questions about your non-adherent cell models with IncuCyte® S3 Cell-by-Cell Analysis. Watch the video now.

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InCytes Publications Newsletter — Vol. 2, 2018

December 11th, 2018

Keep up with the latest IncuCyte® research. Read our summaries of new and notable research articles featuring the IncuCyte Live Cell Analysis System, including hand-picked publications for applications and research areas like immunology, oncology, neurology, and more!

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Video: Oncology — Exploring the hallmarks of cancer with live-cell analysis

December 11th, 2018

The hallmarks of cancer are continually being updated. This constantly evolving picture of tumor biology is helping to shed new light on the behavior of many cancers, as well as providing new pharmacological targets and treatment strategies. Much of this progress has been driven by technological advances, and the last decade has seen huge strides made in the field of live-cell assays, using both traditional 2D techniques and advanced 3D cell culture models.

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InCytes Publication Newsletter — Vol. 1 2018

December 11th, 2018

Read our summaries of new and notable research articles featuring the IncuCyte® Live Cell Analysis System, including hand-picked publications for applications and research areas like immunology, oncology, tumor spheroids, and more!

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In Bad Company: How Dysfunctional Glia Affect Neighboring Neurons

November 14th, 2018

RNA toxicity due to repeat-containing RNA can cause neurological diseases through gain of function. One such RNA repeat disorder is myotonic dystrophy type 1 (DM1), affecting intellectual abilities and central nervous system impairment, among other symptoms. Although a well-known RNA toxicity disorder, the molecular and cellular pathways affected in DM1 brain remain largely unknown.

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