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An Optimized Multiplex Assay for Screening the Functional Capacity of Bispecific T Cell Engager (BiTE) Induced Killing, using Advanced Flow Cytometry

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Cytotoxic T cell lymphocytes become activated upon recognition of cancer or damaged cells, and release effector proteins to initiate the killing of target cells.

Monitoring this process may help in assessing the efficacy of small molecules and biologics, intended for use within the cell therapeutics field.

This poster video describes a simple T cell mediated killing assay workflow, which uses the iQue® Advanced Flow Cytometry Platform, Human T Cell Killing Kit and iQue Forecyt® software. 

Watch the narration of this video poster:

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