“Great equipment. This equipment gives us more possibilities for analysis. The whole cell analysis can be done for vessels such as 6 well plates. The dilution cloning scan allows us to see one single cell. Very useful."
“Great for cell functionality. Easy to use, detailed kinetics of cell function including antibody mediated cell cytotoxicity."
“Great instrument! Saves us a lot of time! This instrument drastically improved our efficiency in being able to transition from total cellular population to single clones during cell line development."
“Awesome! Absolutely useful! The real-time monitoring capacity of the IncuCyte® cell-based assays instrumentation is useful in monitoring cell-growth, cell health, morphology, etc. This is fully automated thereby providing useful data and assessment studies for toxicity, immunoassay, drug delivery/efficacy, and other in vitro evaluation studies on short term and long-term basis while the cells remain undisturbed over these periods of time. It combines the instrument with reagents and image-based analysis into one system!"
"The incucyte is very easy to use. Any trainee can use it after some user's explanations. With this device, we are able to follow the growth of any cells and to have a morphologic view of the cells during time while leaving cells in their usual environment. The software of image analysis included in this device allows to measure a lot of parameters such as the confluence of the culture or the neurites outgrowth. Many other possibilities exist with this device and the new version of the Incucyte ( Incucyte S 3 ) is even more performant."
“The IncuCyte S3 is a crucial support for our cell-based assays. Indispensable. The incucyte S3 is used in our lab to perform kinetic cell assays for the study of the antiproliferative activity and the mechanism of action of compounds. It integrates seamlessly into our screening funnel and has virtually replaced the traditional end-point proliferation assays. The IncuCyte S3 is a very powerful and easy-to-use tool at the same time, which I highly recommend to anyone involved in cell biology research."
“Fantastic technology, no hands on perfectly autonomous. We were users of the Incucyte zoom product previously. We have been interacting with Essen biosciences on our expectations for the next generation of system, and there it is... objective change from one position to another, scheduling between different positions..."
“Our best Cell QC and monitoring system....which makes scientists happy! The new IncuCyte® S3 is really user friendly and a really needed device for our cell QC and monitoring. It allows many formats of cell vessels and the program is very intuitive!”
“Perfect for automated measurement of growth curves. The Incucyte is very easy to use and the software is intuitive. I can quickly set up an experiment to track cell proliferation and walk away while it collects data. It is very customizable and flexible - able to accommodate many different types of plates, and different imaging frequencies, and green and red channels in addition to phase images."
"Easy to use software and product. Great for migration and proliferation assays in the lab. Would recommend to any cell culture user especially those interested in immune therapy."
“Excellent technology and worth the money. We have specifically put our S3 in a controlled environmental chamber. In doing so, we are able to study cell growth and function in tightly controlled conditions without disturbing the cells. This has not been possible prior to the Incucyte technology, and we are very happy with our purchase."
“Instrument that should be a must in each lab. Working at the European Cancer Stem Cell Research Institute, Cardiff University. I was able to perform proliferation assay with GFP+ HeLa cells, apoptotic assay with treated NK92 cells, T-cell killing assay and scratch assay all of them in a time frame of 2 weeks. Always getting my observation in real time and the analysis right away once the experiment was terminated. And everything with remote control."
“Indispensable to our research. Allows us to do virtually any desired in vitro assay at a HT. Additionally, saves a great deal of hands on time and allows for much more reproducible assays. Fits perfectly as part of a core facility platform."
“Wonderful product, a ton of results with just one experiment. It is very user friendly and very helpful if you need to scan a large number of compounds/ cell lines in a short amount of time. The 96 well format allows to do each compound/ drug in triplets over as long as you want, giving you meaningful statistics that would otherwise take a very long time."
“The IncuCyte provides real-time high quality results of the cell culture inside the incubator. Highly recommended to any laboratory doing cell culture. Informs about adhesion, growth, migration, apoptosis, cell proliferation, neuritogenesis, angiogenesis, invasion and many other applications."
"The Essen IncuCyte FLR and ZOOM have been transformative for our research institute. The IncuCyte platform allows us to replace end-point assays of cell viability with high-throughput, kinetic assays in which viability (measured as cell confluence) or morphology is measured as a function of time in response to specific perturbations, so that we can rapidly execute both small- and large-scale studies and comprehensively address the questions fundamental to our research."
"We have been using Essen's IncuCyte technology for the last ten years ranging from their earliest phase contrast reader to the dual fluorescent capable ZOOM. Essen BioScience continues to evolve this product from its first live content incubator based imager through to its full integration into robotic systems. Real time growth kinetic capture is now an obligate tool for characterizing cell lines for use in drug discovery."
"IncuCyte, automated long-term live-cell imaging system, offers a powerful platform for Stem Cell Research. This imaging system in combination with cellular dyes, stem cell specific stains and antibodies is an ideal solution for real time tracking of reprogramming, dissecting basic biology and screening for modulators of pluripotency maintenance and differentiation."
"For the past 5 years, wherever I end up, I have been able to convince my superiors to purchase at least one IncuCyte. I can’t be a cell biologist without it!"
"IncuCyte ZOOM quickly became essential equipment that is used daily for a variety of applications such as cell viability, caspase-activity assays, viral infections and monitoring cell QC. The ease of use, acquisition of kinetic data, reliability, and the robustness of the analysis software are probably the features appreciated most by all. We are extremely pleased with the system and the support from Essen and will likely try to acquire another instrument soon."
"Essen BioScience provides excellent services on the hardware and software for IncuCyte as well as research and technology development. By using IncuCyte, we cut down assay development time because we, as a cell-based assay group, can easily monitor cell doubling time and determine proper cell seeding density, which affects the success of cell based assays. In addition, various reagents developed or referenced by Essen BioScience that are compatible with IncuCyte open up opportunities for developing complex assays with the potential of being used in higher-end high-content imagers/analysis platforms."
"The IncuCyte has proved itself a robust and stable imaging platform, with multiple systems having been in near constant use for greater than 3 years. These systems are used for both product development and manufacture/QC of numerous products and we’ve been pleased with system performance and the service & support provided by Essen."
"The IncuCyte ZOOM is a trusted tool for our cell-based experiments. Automated image collection, in phase-contrast and fluorescent modes, is highly adaptable for our experimental needs. Data processing and quantification are intuitive and user-friendly. The ZOOM has become an integral part of our laboratory."
"The IncuCyte live cell imager is a must have tool when your research requires monitoring cell based assays in real-time. We use our IncuCyte FLR for various applications ranging from standard cell growth monitoring and assay development to full scale HTS drug and siRNA screens for cancer target discovery. Flexibility of the instrument makes it an excellent tool for all these purposes. The microscope has also proven to be extremely robust with minimal encountered downtime despite continuous day and night use which to us is the key feature. I would recommend the instrument to anyone doing cell based screening."
"Our laboratory has had great experiences using the IncuCyte HD and IncuCyte FLR platforms for many years. The precision engineering of the IncuCyte, particularly when coupled with ImageLock culture plates, provides high quality movies that are great for presentations. The software packages provided by Essen Bioscience are user friendly and we have had only positive experiences with their technical support staff and scientists whenever we have had a question or suggestion."
"We have used Essen’s skills and capabilities to provide key data for a number of projects. Essen are customer-focused, have the required sense of urgency, produce data of very high quality and importantly also provide a significant amount of data interpretation to allow us to make timely decisions on project progression."
"Research is in part a lot of hard work, timing and good luck. Lucky for us, Essen BioScience released IncuCyte and took away much of the hard work associated with proliferation and migration assays in our studies under hypoxic conditions. We have two IncuCytes that have been running virtually non-stop for the last four years, and the reliability is remarkable. The newly acquired IncuCyte ZOOM is opening new areas of opportunity in our study . Timing wise, I only wish Essen had released IncuCyte years earlier!"
"Our IncuCyte FLR is widely used here at MCW Cancer Center and has provided valuable data for several manuscripts and grant proposals in the first year that we’ve had it. Our researchers quickly learned the value of monitoring the characteristics of their cell cultures in real-time and performing assays kinetically, which put our instrument in high demand almost immediately."
"I was hesistant as to the capabilities of the IncuCyte however, upon demoing the instrument, I was able to visualize cell behavior that I didn't know was occurring and therefore, quickly purchased an instrument. The IncuCyte and it's software has allowed us to automate cell counting and analysis of cell behavior in a reproducible way. This will revolutionize the way we do cell culture in years to come."
"We sought Essen's considerable expertise in ion channel assays to help us develop a screening method for identification of channel blocking monoclonal antibodies. We were impressed with the depth of technical knowledge applied by Essen's scientists in the set-up and trouble shooting stages, and with the highly rigorous way our assays and experiments were completed."
"The IncuCyte ZOOM is an essential piece of equipment for my studies of cell growth in response to extracellular signals. The kinetic information I get from the IncuCyte is easy-to-visualize and interpret, useful directly as stand-alone data, and also helps inform the design of complementary experiments. Essen has provided outstanding support for installation, operation and updates."
"We’ve been extremely impressed with Essen BioScience, not only in their ability to design and plan our ion channel project work, but also to expedite to a high standard and on schedule. I would thoroughly recommend them as an ion channel discovery partner."
"Essen have provided a rapid turnaround of data for our projects, enabling key SAR to be generated. Communication channels are clear and all requests have been responded to quickly."
"We have been repeatedly impressed with the quality and timely delivery of the biological results."