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Live Cell Assays


Live-cell and phenotypic assays are seeing a rise in popularity as researchers turn to them to ensure the physiological relevance of their results and reveal time-dependent treatment effects. These assays provide real-time morphological and phenotypic insight for pathway and mechanistic studies and can be used to ensure the physiological relevance of results early in the drug discovery process. Whilst rapid, target-specific reductionist assays remain important, phenotypic cell-based assays that enable holistic, integrated cell functions to be measured over the long term (hours to weeks) are now heavily in favor with advanced live cell in vitro co-culture and tissue organoid models becoming increasingly commonplace.

The IncuCyte® Live-Cell Analysis System enables real-time, quantitative live cell assays within your tissue culture incubator. The system allows you to conduct assays and acquire results that would be impossible using single-point and endpoint measures alone. The walk-away automation also allows you to gather more information in a faster or more efficient way.


IncuCyte® applications for live cell assays

Antibody Internalizon Assays

Antibody Internalization Assays

Rapidly quantify antibody internalization using real time live-cell analysis

Scratch Wound Cell Migration and Invasion

Scratch Wound Cell Migration & Invasion

Automatically quantify cell movement across a substrate or through a 3D gel matrix

Chemotaxis

Chemotaxis

Visualize and measure chemotactic cell migration and invasion in real time

Angiogenesis

Angiogenesis

Quantify the formation of vascular structures in relevant co-culture models

Tumor Spheroids

Tumor Spheroids

Monitor and quantify 3D- spheroid formation, growth and shrinkage in real time

Immune cell killing

Immune cell killing

Real-time visualization and fully automated analysis of tumor cell killing

Phagocytosis

Phagocytosis

Automatically quantify and validate phagocytosis using time-lapse imaging

Immune cell clustering

Immune cell clustering

Measure immune cell activation without the need to lift or label your cells

Neurite analysis

Neurite analysis

Long-term, live cell measurements of neurite length and branching

NETosis

NETosis

Automatically visualize and quantify neutrophil extracellular traps in real time


2nd Edition! Live-Cell Analysis Handbook

A comprehensive guide to live-cell analysis inside the incubator

Reserve your copy

Infographic: Live-cell analysis for Immuno-oncology

Understanding immuno-oncology with live-cell analysis

Download yours now
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