Cell Analysis Blog
Cell Analysis Blog

Decoding Cells:

A Cell Analysis Blog

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Capture Protein Expression Changes Over Time in Living Cells

August 23rd, 2018

Immunocytochemistry (ICC) as a basic cell imaging technique has been engrained into every cell biologist’s repertoire. Fluorescently labeled antibodies added onto fixed cells help visualize protein expression in the cells. While traditional ICC yields information on protein localization i.e. where the protein of interest is expressed, a big caveat remains – it is unable to capture protein expression changes over time, the ‘when’ of cellular dynamics.

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The Immune System Reacts to Neurological Stress: Catching Killer T Cells Live in Action

April 6th, 2018

Reactive oxygen species (ROS) have long suffered a bad rap. An overdose of ROS is detrimental and causes a state of oxidative stress. But eliminating them isn’t the answer either as our bodies need ROS for basic survival. Moreover, ROS are essential to immune system function, and act to combat perceived threats to the body. However, a lot is unknown about the role of ROS signaling in immune responses, especially in a diseased state.

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