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The IncuCyte® S3 Live-Cell Analysis System

overview

IncuCyte® S3 Live-Cell Analysis System

Watch the video and see the S3 in action

Select Science Seal of Quality IncuCyte S3

See what your cells are doing and when they do it with the IncuCyte® S3 Live-Cell Analysis System

Derive deeper and more physiologically relevant information about your cells – plus real-time kinetic data. The IncuCyte automatically acquires and analyzes images around the clock, providing an information-rich analysis that is easy to achieve.

Change can happen in an instant.  Whether simply assaying cell health or more complex processes like migration, invasion, or immune cell killing, see what happened and when—without ever removing your cells from the incubator.

Never miss powerful insights again, with the IncuCyte® S3 live-cell analysis system, reagents, and consumables.

request a quote or demo    Watch the applications video

reviews Read SelectScience reviews now

2nd Edition! Live-Cell Analysis Handbook

A comprehensive guide to live-cell analysis inside the incubator

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InCytes Publications eNewsletter

Featuring new and notable IncuCyte® publications

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live-cell analysis

What is live-cell analysis and what are the benefits?

Combine information-rich, image-based analysis with the convenience and throughput of microplate assays.

HT-1080 Cell Invasion through Matrigel

 

Derive deeper insights with real-time live-cell analysis

Derive deeper insights with real-time live-cell analysis. (A) Automatically acquire images over time, (B) use IncuCyte® VesselView to view images of all locations in the vessel at once and quickly assess experimental results, plus zoom in on images of interest (C) automatically identify regions of interest via masks (D) generate presentation-ready timelapse graphs, and (E) view all 96- or 384-well kinetic trends at once with IncuCyte® PlateGraph and export data to calculate EC50 or IC50 response values.

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Ask new questions

  • Flexible assay platform enables experiments that were not previously possible
  • Kinetic, image-based measurements provide answers to everyday and unique scientific questions

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Get new answers

  • Real-time continuous analysis means you never miss a data point
  • Profile cell-specific and time-dependent biological activity
  • Visualize and validate results with images and movies

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Improve productivity

  • Add IncuCyte proprietary reagents directly to cells, and walk away as IncuCyte automatically acquires and analyzes images
  • Multiplex measurements in 96- and 384-well assay formats
  • Accommodate multiple users and applications simultaneously

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Protect your cells

  • Perform analysis without removing cells from the incubator
  • Maintain cell health and morphology with non-perturbing reagent formulations

features

IncuCyte S3 — Key Features

IncuCyte transforms research into a complete and powerful workflow that supports your entire research team — day and night.

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Simple, flexible sample prep

Utilize IncuCyte reagents with your choice of vessels for minimal cell perturbance

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Set up & walk away

Set up automated acquisition and analysis parameters with confidence – no need to pre-define the assay endpoint

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Acquire images as long as you like

Automatically acquire images for hours, days, or weeks

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View and analyze in real-time

Powerful image visualization and analysis tools enable real-time decision-making

Support for multiple users

Support for multiple users

  • IncuCyte accommodates up to six microplates at a time
  • Users can schedule experiments at different image acquisition frequencies and magnifications in parallel
  • Remote, networked access with unlimited, free licenses

Simple, flexible sample prep

  • Compatible with a wide range of culture vessels and applications
  • Utilize IncuCyte reagents for minimal cell perturbance and maximum efficiency

Download the IncuCyte S3 Vessel Compatibility List

Simple, flexible sample prep

Set up & walk away

Set up & walk away

  • Brand new user interface for simple and flexible experimental set up
  • Track experimental conditions from setup through analysis

Acquire images over days or weeks

  • Leave your cells undisturbed in the incubator during image acquisition
  • Unique optical design – cells remain stationary while optics move
  • Multiple imaging modes – HD phase plus red and green fluorescence

Acquire images over days or weeks

View and Analyze in real-time...or later

View and Analyze in real-time...or later

  • Efficient and reproducible image analysis
  • Powerful visualization of images and timecourses

Other key features


Speed and Sensitivity In Mind

  • CMOS camera and efficient optics enable long-term live-cell imaging and analysis
  • 16 total core processors allowing for fast image processing and data analysis

Data Protection & Storage

  • Includes 16.4TB of RAID hard drive data storage, which can be further extended with the 32.7TB IncuStore S

LCD Control Panel

  • Monitor and perform basic status checks and operations from the front panel of the IncuCyte S3 System controller unit

applications

More than 20 IncuCyte® Applications

More than 20 IncuCyte® Applications!

The IncuCyte S3 System is used for real-time cell monitoring and surveillance, cell health and viability, migration and invasion, plus a wide range of phenotypic cell-based assays. With a rapidly growing collection of over 1,000 peer reviewed articles, new applications using the IncuCyte are being published continuously.

Watch the applications video     SEE OUR Full LIST OF APPLICATIONS

reviews

See what your peers are saying about the IncuCyte® System

The IncuCyte Live-Cell Analysis System is the first real-time system that automatically captures and analyzes images of living cells around-the-clock for days, weeks, or months, while cells remain undisturbed inside a standard tissue culture incubator. Kinetic, image-based measurements ensure you never miss a relevant response.

"Our best Cell QC and monitoring system...which makes scientists happy!"
— Cécile Cazaubon, Novartis Pharma AG

"Excellent technology and worth the money."
— Adam Case, University Of Nebraska Medical Center

"Indispensable to our research."
— Ali Talebi, KU Leuven

Read IncuCyte Testimonials Now    Read Select Science Reviews Now

Ordering

Ordering Information

Product Description Cat. No.
IncuCyte® S3 Live-Cell Analysis System Includes image acquisition and analysis system with 4x, 10x, 20x objectives, controller, and unlimited software licenses for standard acquisition and basic analyzer 4647 Request a quote or demo
IncuStore® S Storage Unit Additional 32.7 TB storage for IncuCyte S3 extends storage to 49 TB in total 4689 Learn more
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IncuCyte® Base Software

IncuCyte S3 software makes the process of acquiring, viewing, analyzing and sharing images of living cells easier than ever before

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IncuCyte® S3 Software (v2018A)

The new IncuCyte® S3 Software update (V2018A) is now available for the IncuCyte® S3 Live-Cell Analysis System to provide you with new features that have been highly requested by our users plus more versatility when using the Spheroid Software Module to acquire and analyze images of three-dimensional tumor spheroids.

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IncuCyte® ClearView 96-well Chemotaxis Plate

Each well of a ClearView plate provides an optically clear surface for label-free imaging and analysis of chemotactic cell migration using the IncuCyte® Live-Cell analysis system.

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IncuCyte® Chemotaxis Software (Cat No 9600-0015)

An add-on software module for the IncuCyte ® Live-Cell Analysis System. Analyze label-free and fluorescently-labelled chemotactic cell migration images acquired using the ClearView Cell Migration Plate.

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IncuCyte® NeuroPrime Cell Kit (Cat No 4585)

A complete solution for performing kinetic, live-cell imaging of 96-well co-culture assays utilizing primary rat neurons and astrocytes. Supplied as 1 vial (0.45mL) NeuroLight Red Lentiviral Reagent (synapsin promoter), 1 vial (2 x 10^6 cells) IncuCyte® rCortical Neurons (cryopreserved rat cortical neurons), 1 vial (2 x 10^6 cells) IncuCyte® rAstrocytes (cryopreserved rat astrocytes)

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IncuCyte® Extended Warranty & Software Updates

IncuCyte® Extended Service Warranty Includes 1 year coverage of all Parts, Labor and base software updates (excluding new modules)

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IncuCyte® NeuroTrack Software Module (Cat No 9600-0010)

IncuCyte® software module to enable measurement of neurite dynamics

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IncuCyte® Fluorescence Calibration Standards Kit (Cat No 4515)

The fluorescence calibration kit is used to calibrate IncuCyte ZOOM® systems which have fluorescence capability. The kit contains reagent sufficient for multiple calibrations as well as three calibration slides. The calibration slides are disposable and should be used only once. It is recommended that the instrument is recalibrated twice a year.

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IncuCyte® IncuStore S

Ideal if you use your IncuCyte intensively as it keeps data on-line and at your fingertips for longer. The RAID 6 configuration of 8 x 6TB hard disks protects all data.

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Intellicyt® iQue Screener PLUS

The Intellicyt® iQue Screener PLUS enables rapid, multiperimeter analysis of cells and beads in suspension.

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Directing cell migration using micro-patterned and dynamically adhesive polymer brushes View publication
Phenotypic modifications in ovarian cancer stem cells following Paclitaxal treatment View publication
Functional screening assays with neurons generated from pluripotent stem cell-derived neural stem cells View publication
Pharmacologic characterization of a kinetic in vitro human co-culture angiogenesis model using clinically relevant compounds View publication
ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation View publication
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