Morphological and Phenotypic Live-Cell Assays


Live-cell and phenotypic assays are seeing a rise in popularity as researchers turn to them to ensure the physiological relevance of their results and reveal time-dependent treatment effects. These assays provide real-time morphological and phenotypic insight for pathway and mechanistic studies and can be used to ensure the physiological relevance of results early in the drug discovery process. Whilst rapid, target-specific reductionist assays remain important, phenotypic cell-based assays that enable holistic, integrated cell functions to be measured over the long term (hours to weeks) are now heavily in favor with advanced live cell in vitro co-culture and tissue organoid models becoming increasingly commonplace.

The Incucyte® Live-Cell Analysis System enables real-time, quantitative live cell assays within your tissue culture incubator. The system allows you to conduct assays and acquire results that would be impossible using single-point and endpoint measures alone. The walk-away automation also allows you to gather more information in a faster or more efficient way.


Antibody Internalizon Assays

Antibody Internalization Assays

Rapidly quantify antibody internalization using real time live-cell analysis

Scratch Wound Cell Migration and Invasion

Scratch Wound Cell Migration & Invasion

Automatically quantify cell movement across a substrate or through a 3D gel matrix

Chemotaxis

Chemotaxis Cell Migration & Invasion

Visualize and measure chemotactic cell migration and invasion in real time

Tumor Spheroids

Tumor Spheroids

Monitor and quantify 3D- spheroid formation, growth and shrinkage in real time

Immune cell killing

Immune Cell Killing

Real-time visualization and fully automated analysis of tumor cell killing

Phagocytosis

Phagocytosis

Automatically quantify and validate phagocytosis using time-lapse imaging

Immune cell clustering

Immune Cell Clustering

Measure immune cell activation without the need to lift or label your cells

Neurite analysis

Neurite Analysis

Long-term, live cell measurements of neurite length and branching

NETosis

Neuronal Activity & Function

Record activity from over a thousand cells to study changes in neuronal network activity and connectivity

NETosis

NETosis

Automatically visualize and quantify neutrophil extracellular traps in real time


4th Edition! Live-Cell Analysis Handbook

A guide to real-time live-cell imaging & analysis


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Application Note:

Gain additional insights into the mechanism of immune cell killing by combining live cell analysis and flow cytometry into a single workflow

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