Publications - Discoveries and Innovations from Incucyte

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Displaying 327 results out of a total of 2729 publications.

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Targeting the podocyte to treat glomerular kidney disease
Lal MA,Young KW,Andag U,
Drug Discov. Today, pii: S1359-6446(15)00233-0, 2015

Researchers at AstraZeneca and Evotec use IncuCyte™ to functionally validate and assess the potency of screening hits in an ex vivo model of diabetic nephropathy revealing novel opportunities for kidney-specific therapeutics.

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Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1
Li, CW;Lim, SO;Chung, EM;Kim, YS;Park, AH;Yao, J;Cha, JH;Xia, W;Chan, LC;Kim, T;Chang, SS;Lee, HH;Chou, CK;Liu, YL;Yeh, HC;Perillo, EP;Dunn, AK;Kuo, CW;Khoo, KH;Hsu, JL;Wu, Y;Hsu, JM;Yamaguchi, H;Huang, TH;Sahin, AA;Hortobagyi, GN;Yoo, SS;Hung, MC;
Cancer Cell, Cancer Cell, 33(2):187-201.e10, 2018
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Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC
Dai, Y;Wei, Q;Schwager, C;Hanne, J;Zhou, C;Herfarth, K;Rieken, S;Lipson, KE;Debus, J;Abdollahi, A;
Radiat Oncol, Radiat Oncol, 13(1):1, 2018
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Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma
Hanes, R;Grad, I;Lorenz, S;Stratford, EW;Munthe, E;Reddy, CC;Meza-Zepeda, LA;Myklebost, O;
Oncotarget, Oncotarget. 2016 Jul 9., 2016
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Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1c259T cells in Synovial Sarcoma
D'Angelo, SP;Melchiori, L;Merchant, MS;Bernstein, DB;Glod, J;Kaplan, RN;Grupp, SA;Tap, WD;Chagin, K;Binder, GK;Basu, S;Lowther, DE;Wang, R;Bath, N;Tipping, A;Betts, G;Ramachandran, I;Navenot, JM;Zhang, H;Wells, DK;Van Winkle, E;Kari, G;Trivedi, T;Holdich, T;Pandite, LN;Amado, R;Mackall, CL;
Cancer Discov, Cancer Discov, ():, 2018
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Discoidin Domain Receptor 2 Signaling Regulates Fibroblast Apoptosis Through PDK1/Akt
Jia, S;Agarwal, M;Yang, J;Horowitz, JC;White, ES;Kim, KK;
Am. J. Respir. Cell Mol. Biol., Am. J. Respir. Cell Mol. Biol., ():, 2018
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Functional proteomics and deep network interrogation reveal a complex mechanism of action of midostaurin in lung cancer cells
Ctortecka, C;Palve, V;Kuenzi, BM;Fang, B;Sumi, NJ;Izumi, V;Novakova, S;Kinose, F;Remsing Rix, LL;Haura, EB;Koomen, JM;Rix, U;
Mol. Cell Proteomics, Mol. Cell Proteomics, ():, 2018
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SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer
Fang, Z;Cao, B;Liao, JM;Deng, J;Plummer, KD;Liao, P;Liu, T;Zhang, W;Zhang, K;Li, L;Margolin, D;Zeng, SX;Xiong, J;Lu, H;
Elife, Elife, 7():, 2018
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A versatile drug delivery system targeting senescent cells
Muoz-Espn, D;Rovira, M;Galiana, I;Gimnez, C;Lozano-Torres, B;Paez-Ribes, M;Llanos, S;Chaib, S;Muoz-Martn, M;Ucero, AC;Garaulet, G;Mulero, F;Dann, SG;VanArsdale, T;Shields, DJ;Bernardos, A;Murgua, JR;Martnez-Mez, R;Serrano, M;
EMBO Mol Med, EMBO Mol Med, ():, 2018
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Bax/Tubulin/Epithelial-Mesenchymal Pathways Determine the Efficacy of Silybin Analog HM015k in Colorectal Cancer Cell Growth and Metastasis
Amawi, H;Hussein, N;Ashby, C;Alnafisah, R;Sanglard, L;Manivannan, E;Karthikeyan, C;Trivedi, P;Eisenmann, K;Robey, R;Tiwari, A;
Front. Pharmacol., Front. Pharmacol., 9():, 2018
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