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Displaying 2291 results out of a total of 2291 publications.

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Combined inhibition of mTOR and CDK4/6 is required for optimal blockade of E2Ffunction and long term growth inhibition in estrogen receptor positive breast cancer
Michaloglou, C;Crafter, C;Siersbk, R;Delpuech, O;Curwen, JO;Carnevalli, LS;Staniszewska, AD;Polanska, UM;Cheraghchi-Bashi, A;Lawson, M;Chernukhin, I;McEwen, R;Carroll, JS;Cosulich, SC;
Mol. Cancer Ther., Mol. Cancer Ther., ():, 2019
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miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy
Huang, Q;Xia, J;Wang, L;Wang, X;Ma, X;Deng, Q;Lu, Y;Kumar, M;Zhou, Z;Li, L;Zeng, Z;Young, KH;Yi, Q;Zhang, M;Li, Y;
J Hematol Oncol, J Hematol Oncol, 11(1):58, 2019
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Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
Zaretsky, JM; Garcia-Diaz, A; Shin, DS; Escuin-Ordinas, H;Hugo, W; Hu-Lieskovan, S;Torrejon, DY; Abril-Rodriguez, G; Sandoval, S; Barthly, L; Saco, J; Homet Moreno, B; Mezzadra, R; Chmielowski, B; Ruchalski, K; Shintaku, IP; Sanchez, PJ; Puig-Saus, C; Cherry, G; Seja , E; Kong, X; Pang, J; Berent-Maoz, B; Comin-Anduix, B; Graeber, TG; Tumeh, PC; Schumacher, TN; Lo, RS; Ribas A;
N Engl J Med, N Engl J Med.2016 Jul 13, 2016
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Cadm1 is a metastasis susceptibility gene that suppresses metastasis by modifying tumor interaction with the cell-mediated immunity
Faraji F, Pang Y, Walker RC, Nieves Borges R, Yang L, Hunter KW
PLoS Genet, 8(9):e1002926, 2012
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A Noncanonical Frizzled2 Pathway Regulates Epithelial-Mesenchymal Transition and Metastasis
Gujral, Taranjit S et al
Cell, 159, 844--856, 2014

A panel of IncuCyte migration assays were used to functionally characterize and dissect a novel signaling pathway regulating cell migration and metastasis. Highly detailed gene overexpression, shRNA knock down and pharmacological inhibition studies revealed a novel Fzd2-Fyn-Stat3 signaling axis regulating cell migration.

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Multiple Molecular Subtypes of Triple-Negative Breast Cancer Critically Rely on Androgen Receptor and Respond to Enzalutamide In Vivo
Barton, Valerie N et al
Molecular cancer therapeutics, 14, [Epub ahead of print], 2015, 2015
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Reactivation of mutant-EGFR degradation through clathrin inhibition overcomes resistance to EGFR tyrosine kinase inhibitors
Mnard, L;Floc'h, N;Martin, MJ;Cross, DA;
Cancer Res., Cancer Res., ():, 2018
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FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3
Jozwik, KM;Chernukhin, I;Serandour, AA;Nagarajan, S;Carroll, JS;
Cell Rep, Cell Rep, 50 (10): 2715-2723, 2016
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Merkel cell polyomavirus small T antigen drives cell motility via Rho-GTPase-induced filopodia formation
Stakaityt?, G;Nwogu, N;Dobson, SJ;Knight, LM;Wasson, CW;Salguero, FJ;Blackbourn, DJ;Blair, GE;Mankouri, J;Macdonald, A;Whitehouse, A;
J. Virol., J. Virol., ():, 2018
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Gaining Insight In The Selectivity And Plasma-Liquid Chemistry For Plasma Treatment Of Cancer
Van Boxem, W;Van der Paal, J;Deben, C;Verlackt, C;Smits, E;Bogaerts, A;
Clinical Plasma Medicine, Clinical Plasma Medicine, 9():30, 2019
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