Publications - Discoveries and Innovations from Incucyte

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Displaying 2729 results out of a total of 2729 publications.

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Abstract B12: Co-targeting PTEN-defined TNBC with p110beta-isoform specific inhibitor and PARP inhibitor BMN 673: A predictive context to sensitize PARP inhibitors
Dey, N;Carlson, JH;De, P;Leyland-Jones, B;
Molecular Cancer Research, Mol Cancer ResFebruary 201614;B12, 2016
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Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I
Robke, L;Futamura, Y;Konstantinidis, G;Wilke, J;Aono, H;Mahmoud, Z;Watanabe, N;Wu, Y;Osada, H;Laraia, L;Waldmann, H;
Chem. Sci., Chem. Sci., 9(11):3014-3022, 2018
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Targeting the podocyte to treat glomerular kidney disease
Lal MA,Young KW,Andag U,
Drug Discov. Today, pii: S1359-6446(15)00233-0, 2015

Researchers at AstraZeneca and Evotec use IncuCyte™ to functionally validate and assess the potency of screening hits in an ex vivo model of diabetic nephropathy revealing novel opportunities for kidney-specific therapeutics.

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A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, et al
Cancer Res, 72(11):2822–32, 2012
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Glycoprotein 90K Promotes E-Cadherin Degradation in a Cell Density-Dependent Manner via Dissociation of E-Cadherin-p120-Catenin Complex
Park, SY;Yoon, S;Sun, EG;Zhou, R;Bae, JA;Seo, YW;Chae, JI;Paik, MJ;Ha, HH;Kim, H;Kim, KK;
Int J Mol Sci, Int J Mol Sci, 18(12):, 2018
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Combinatorial therapy with three-dimensionally cultured adipose-derived stromal cells and self-assembling peptides to enhance angiogenesis and preserve cardiac function in infarcted hearts
Kim, JH;Park, Y;Jung, Y;Kim, SH;Kim, SH;
J Tissue Eng Regen Med, J Tissue Eng Regen Med, 11(10):2816-2827, 2017
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BET inhibitors as novel therapeutic agents in breast cancer
Ocaa, A;Nieto-Jimnez, C;Pandiella, A;
Oncotarget, Oncotarget, 8(41):71285-71291, 2018
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ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms
Zaidi N, Royaux I, Swinnen JV, Smans K
Mol Cancer Ther, 11(9):1925–35, 2012
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Glucocorticoid signaling regulates cell invasion and migration in the human first-trimester trophoblast cell line Sw.71
Kisanga, EP;Tang, Z;Guller, S;Whirledge, S;
Am. J. Reprod. Immunol., Am. J. Reprod. Immunol., ():e12974, 2018
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Immuno-Oncology Integrative Networks: Elucidating the Influences of Osteosarcoma Phenotypes
Sharma, A;Capobianco, E;
Cancer Informatics, Cancer Informatics, 16(1):117693511, 2017
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