Commonly used approaches
In vitro assays for cell migration and chemotaxis are necessary for both basic-research and drug discovery. The table below shows capabilities and challenges of some common approaches.
Existing Boyden Chambers | Microfluidic Devices | IncuCyte® Chemotaxis Cell Migration and Invasion | |
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Chemotactic migration | ![]() |
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Migration in the absence of chemotactic gradients | ![]() |
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Low cell usage (<5,000 per well) | ![]() |
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Suitable for non-adherent cells | ![]() |
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Migration across a surface | ![]() |
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Invasion through a 3D gel matrix | ![]() |
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Integrated quantitation | ![]() |
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Integrated cell observation | ![]() |
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Precision, reproducibility | ![]() |
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96-well throughput or higher | ![]() |
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Kinetic read-out | ![]() |
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Label-free | ![]() |
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Workflow: set up and walk away | ![]() |
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