EBOOK

The Future of Drug Discovery - Live 3D Cell Analysis

Advanced cell models like spheroids and organoids are growing in popularity for modeling diseases in basic research and drug development. Traditional workflows for characterizing 3D cultures are limited in their ability to provide real-time image-based and kinetic data over long time-course studies. Live-cell imaging and analysis technologies allow scientists to continuously monitor complex 3D cell systems.

This eBook spotlights some of the latest studies that use 3D cell models, including topics on cancer drug screening, intestinal transmission of SARS-CoV-2, and immunotherapy. Additionally, there is a detailed discussion of live-cell analysis technologies and assays, like Incucyte® Live-Cell Analysis System, for real-time monitoring of cell health, behavior and morphology.

Featured studies include:

Study: Cell Stiffness may Indicate Likelihood of Cancer Metastasis
3D “Squeeze” Helps Adult Cells Become Stem Cells
Cancer Screen with Spheroids Shows Promise Therapeutically
Immunotherapy Screening using Immune-Enhanced Organoids
SARS-CoV-2 Infection of Gut Organoids Bolsters Case for Intestinal Transmission

Live-cell analysis topics include:

Live-Cell Monitoring: Optimizing Workflows for Advanced Cell Models
Real-Time Live-Cell Analysis of Multi-Spheroid, Co-Cultured, 3D Tumor Assays

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