Live-Cell Kinetic Assays

OVERVIEW

We recognize that buying an IncuCyte and developing and running assays is not for everyone. Using our biotechnology services team at Essen, we offer customer access to our CellPlayer^TM family of live-cell assays on a fee for service model.

NEW CELL PLAYER ANGIOGENESIS ASSAY

Angiogenesis, the formation of new blood vessels from pre-existing vasculature, is a key biological process involved in numerous physiological and pathological events including wound healing, tumor growth and diabetic retinopathy. We have developed a kinetic, primary cell, co-culture assay model by labeling endothelial cells with GFP, reading with IncuCyte FLR, and integrating custom analysis metrics which quantify tube formation and branching over time. The kinetic readout enhances mechanistic pathway analysis, assay dynamic range and compound evaluation paradigms.

See Angiogenesis movies taken with IncuCyte
Read more about kinetic angiogenesis assays and live-cell kits

NEW CELL PLAYER MIGRATION ASSAY

Cell migration is a fundamental, yet complex biological process involved in almost every aspect of human biology. In a healthy individual, it is critical to our immune response and wound healing. Cell migration also plays critical roles in disease, specifically in the areas of asthma, rheumatoid arthritis, tumor growth, as well as atherosclerosis and vascular disease. We have developed an automated, 96-well, kinetic, non-labeled, cell migration assay around our IncuCyte platform. Using this assay we can quantify cell migration in time, without labels, and without removing cells from the incubator.

See Cell Migration movies taken with IncuCyte
Read more about kinetic cell migration on IncuCyte