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Scientific Articles

article chemotaxis

Kinetic, Automated, Image-based Measurement of Chemotaxis

hemotactic migration and invasion play an essential role in many normal and pathological processes including immune response, cell differentiation and tumor metastasis. Methods to study factors that regulate the directional migration of cells typically employ modifications of Boyden chamber assays. Boyden chamber assays consist of an upper and lower chamber separated by a porous filter, allowing for the diffusion of a chemotactic agent.

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interview

Interview: Molecule Orientated Discovery — Driving Wound Recovery

People get wounds for various reasons. In addition to injury from falls and burns, wounds to organs such as ulcers of the digestive tract are common. However, many mysteries still remain in the wound recovery process. Steady progress is being made by research into pharmaceuticals that promote recovery...

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cell culture

The Effects of Temperature and Atmospheric Perturbation During Cell Culture: The Silent Variables

The environmental confines of a laboratory incubator provide a controlled temperature and level of atmospheric carbon dioxide (CO2), in an attempt to replicate the cells’ native conditions; for mammalian cell culture, this mimics a cell’s environs in the host’s body – no small feat! This includes an aseptic environment with a specific atmospheric mix, maintained within a tightly controlled temperature and humidity range...

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immuno-oncology article

In Vitro Assays for Immuno-Oncology Research

In the search for precision cancer treatments, researchers are developing new techniques and technologies that harness the body's natural defenses to target and eradicate cancer cells. The transformative research leading to these new methods are thanks to dedicated immuno-oncology scientists who are interrogating the subtle and, oftentimes, hidden interactions between cancer and the host’s immune system...

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