Commonly used approaches
In vitro assays for cell migration and chemotaxis are necessary for both basic-research and drug discovery. The table below shows capabilities and challenges of some common approaches.
Existing Boyden Chambers | Microfluidic Devices | IncuCyte® Chemotaxis Cell Migration and Invasion | |
---|---|---|---|
Chemotactic migration | |||
Migration in the absence of chemotactic gradients | |||
Low cell usage (<5,000 per well) | |||
Suitable for non-adherent cells | |||
Migration across a surface | |||
Invasion through a 3D gel matrix | |||
Integrated quantitation | |||
Integrated cell observation | |||
Precision, reproducibility | |||
96-well throughput or higher | |||
Kinetic read-out | |||
Label-free | |||
Workflow: set up and walk away |